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 Übersetzung für 'N-methyl-D-aspartate' von Englisch nach Deutsch
pharm.
N-methyl-D-aspartate antagonists <NMDA antagonists>
N-Methyl-D-Aspartat-Antagonisten {pl} <NMDA-Antagonisten>
pharm.
N-methyl-D-aspartate-receptors <NMDARs>
N-Methyl-D-Aspartat-Rezeptoren {pl} <NMDA-R>
2 Übersetzungen
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Anwendungsbeispiele Englisch
  • Glutamate receptor, ionotropic, N-methyl D-aspartate-like 1B, also known as GRINL1B, is a human gene. The protein encoded by this gene is a subunit of the NMDA receptor.
  • The theory between immune system changes and associated PPP onset has been largely spurred by higher than average occurrences of PPP in individuals also experiencing immunologic complications, such as anti-N-methyl-D-aspartate (NMDA) receptor encephalitis and autoimmune thyroid disorders, as well as the onset of PPP occurring at the same time the body is experiencing higher immune responses (a natural process associated with the period immediately following childbirth).
  • A hippocampal transcriptome analysis was profiled on knockout mice, showing the increased activity of N-methyl-D-aspartate receptors.
  • DLGAP2 has been shown to interact with DLG4, the canonical synapse marker protein, which in turn binds to N-Methyl-d-aspartate (NMDA) receptors and Shaker-type K+ channels.
  • Overt activation of N-methyl-D-aspartate (NMDA) receptors following brain injuries can lead to calcium entry which triggers neuronal death via the mechanisms of excitotoxicity.

  • Memory disruptions by alcohol leading to blackout have been linked to inhibition of long-term potentiation, particularly in the hippocampus, by affecting gamma-Aminobutyric acid (GABA) and N-methyl-D-aspartate neurotransmission.
  • In primary cultures of rat cortical neurons, the inhibition of PDE2A by EHNA potentiates NMDA ("N"-methyl-D-aspartate) receptor activated increase in cGMP, but has no effect on cAMP concentrations.
  • A treatment of sodium benzoate, which binds to glycine and forms hippurate, and dextromethorphan, which weakly inhibits the N-methyl-D-aspartate receptors that glycine acts on has been shown to improve outcomes in select cases where the disorder is present in attenuated form.
  • In addition, alcohol also inhibits the activity of "N"-methyl-D-aspartate receptors (NMDARs).
  • For example, group I mGluRs are known to increase the activity of "N"-methyl-"D"-aspartate receptors (NMDARs), mGluRs tend to protect neurons from excitotoxicity, and in neurotoxicity and neuroprotection.

  • In addition there is a synergistic effect with endogenous glutamate and N-Methyl-D-aspartate receptor agonists that contribute to the excitotoxicity.
  • The CNS homolog is glutamate and its receptors, and one of special significance is the N-methyl-D-aspartate (NMDA) receptor.
  • N-methyl-D-aspartate (NMDA) receptor blockers such as memantine may be of benefit but the evidence is less conclusive than for AChEIs.
  • They showed that at least some of the neural cell death caused by hypoxia-ischaemia is mediated by excess production of the excitatory neurotransmitter glutamate, and that pharmacological blockade of the N-methyl-D-aspartate receptor could provide good protection against hypoxic damage.
  • Ethanol is known to activate aminobutyric acid type A (GABAA) and inhibit N-methyl-D-aspartate (NMDA) glutamate receptors, which are both implicated in essential tremor pathology and could underlie the ameliorative effects.

  • Two hypotheses for the explanation of umami taste transduction have been introduced: the first posits that the umami taste is transduced by an N-methyl-D-aspartate (NMDA) type glutamate ion channel receptor; the second posits that the taste is transduced by a metabotropic type glutamate receptor (taste-mGluR4).
  • Glutamate [...] receptor subunit epsilon-2, also known as "N"-methyl D-aspartate receptor subtype 2B (NMDAR2B or NR2B), is a protein that in humans is encoded by the "GRIN2B" gene.
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Enthält Übersetzungen von der TU Chemnitz sowie aus Mr Honey's Business Dictionary (nur Englisch/Deutsch).
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