⇄SuchrichtungÜbersetzung für 'scFv' von Englisch nach Deutsch
single-chain variable fragment <scFv>
variables Einzelkettenfragment {n} <scFv-Fragment>
1 Übersetzung
Neue Wörterbuch-Abfrage: Einfach jetzt tippen!
Anwendungsbeispiele Englisch
  • The binding region is a modified single-chain variable fragment (scFv), and the rest of the protein can be constructed from the fragment crystallizable region (Fc) and the hinge region of an immunoglobulin G1 (IgG1).
  • The variable regions of the heavy and light chains can be fused together to form a single-chain variable fragment (scFv), which is only half the size of the Fab fragment, yet retains the original specificity of the parent immunoglobulin.
  • Nine years later, Fukuda and colleagues chose mRNA display method for "in vitro" evolution of single-chain Fv (scFv) antibody fragments.
  • A single-chain variable fragment (scFv) is not actually a fragment of an antibody, but instead is a fusion protein of the variable regions of the heavy (VH) and light chains (VL) of immunoglobulins, connected with a short linker peptide of ten to about 25 amino acids.
  • ” A CAR typically comprises an antibody fragment (scFv) to recognize the cancer and a modular signaling domain to activate the T cell and promote T cell multiplication and persistence.
  • The single chain variable antibody fragment (scFv) ER-5 was recently created by mutating earlier used scFVs which were used against other Mexican scorpion toxins.
  • Two main strategies have been described to engineer the scFv fragments.
  • The same heavy and light variable chains used for scFv construction can be used in the construction of Fab.
  • This picomolar affinity binding results in the diseased cells becoming coated in CD3 co-receptor specific scFv antibody fragments that constitute the ImmTAC effector function.
  • Alternatives for the antibody targeting component now include multiple smaller antibody fragments like diabodies, Fab, scFV, and bicyclic peptides.
  • These include chemically linked Fabs, consisting of only the Fab regions, and various types of bivalent and trivalent single-chain variable fragments (ScFvs).
  • His group has demonstrated that a synthetically prepared cell-surface glycosphingolipid can be utilized as a panning reagent to identify fully human single chain antibodies (scFvs) that are selective for melanoma and breast tumor cells.
© dict.cc English-German dictionary 2023
Enthält Übersetzungen von der TU Chemnitz sowie aus Mr Honey's Business Dictionary (nur Englisch/Deutsch).
Links auf das Wörterbuch oder auch auf einzelne Übersetzungen sind immer herzlich willkommen!