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- It is a hapten used in vaccine preparation. Dinitrophenyl does not elicit any immune response on its own and it does not bind to any antigen.
- The assay uses hapten-labelled nucleotides in a primer extension reaction.
- An explicit example is a hapten. Haptens are low-molecular-weight compounds that may be bound by antibodies, but cannot elicit an immune response.
- Digoxin Immune Fab is the antigen binding fragment of polyclonal antibodies raised to Digitalis derivative as a hapten bound to a protein and is used for the reversal of life-threatening digoxin or digitoxin toxicity.
- One classical clinical model for a hapten reaction is contact dermatitis.
- The beginning of the pretargeting concept was based on bispecific antibodies which were able to bind a specific target antigen and a radiolabelled hapten.
- The major antigenic determinant of penicillin hypersensitivity is its metabolite, penicilloic acid, which reacts with proteins and serves as a hapten to cause an immune reaction.
- Dextran 1 is a hapten inhibitor that greatly reduces the risk for anaphylactic reactions when administering dextran.
- To name a few, deep-brain stimulation, agonist/antagonist implants and hapten conjugate vaccines.
- Hybridization is followed by single-base extension with hapten-labeled dideoxynucleotides.
- First, the probe is labeled with either direct or indirect labeling strategy: hapten-modified nucleotides are used in indirect labeling, and fluorophore-modified nucleotides are used in direct labeling.
- Once the body has generated antibodies to a hapten-carrier adduct, the small-molecule hapten may also be able to bind to the antibody, but it will usually not initiate an immune response; usually only the hapten-carrier adduct can do this.
- Contact allergens are essentially soluble haptens (low in molecular weight) and, as such, have the physico-chemical properties that allow them to cross the stratum corneum of the skin.
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Enthält Übersetzungen von der TU Chemnitz sowie aus Mr Honey's Business Dictionary (nur Englisch/Deutsch).
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