Übersetzung für 'Nonsense-Codon' von Englisch nach Deutsch

nonsense codon

Nonsense-Codon {n}biol.

• Usually a nonsense codon (stop codon) or a four-base codon are used.
• In a study of 65 individuals affected with EvC, mutations in the EVC gene were found in 20 of them, and primarily attributed to a frameshift resulting in a nonsense codon.
• In addition, it was found that an amber mutation produces a "nonsense codon" within a gene that causes polypeptide chain termination during translation.
• The organism which expresses such a synthetase can then be genetically programmed to incorporate the unnatural amino acid into a desired protein in the usual way, with the nonsense codon now coding for the unnatural amino acid.
• It has been observed that the ability of a nonsense codon to cause mRNA degradation depends on its relative location to the downstream sequence element and associated proteins.

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