22 Übersetzungen
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- A few progestins have weak estrogenic activity. These include the 19-nortestosterone derivatives norethisterone, noretynodrel, and tibolone, as well as the norethisterone prodrugs The estrogenic activity of norethisterone and its prodrugs are due to metabolism into ethinylestradiol.
- Norethandrolone has relatively high estrogenic activity via transformation by aromatase into the potent estrogen ethylestradiol.
- The same study associated this compound with estrogenic activity in vitro.
- Androstenediol possesses potent estrogenic activity, similarly to DHEA and 3β-androstanediol.
- PEP has antigonadotropic and functional antiandrogenic effects due to its estrogenic activity.
- Fenofibric acid was one of the 12 compounds identified in sludge samples taken from 12 wastewater treatment plants in California that were associated with estrogenic activity in in vitro.
- Quinbolone, via boldenone, can be transformed into estrogens, and hence may have some estrogenic activity.
- While the rate of aromatization is reduced relative to that for testosterone or methyltestosterone, the estrogen produced is metabolism-resistant and hence metandienone retains moderate estrogenic activity.
- The stilbestrols, which are structurally but not synthetically related to ("E")-stilbene, exhibit estrogenic activity.
- Drospirenone has no estrogenic activity and no appreciable glucocorticoid or antiglucocorticoid activity.
- Desogestrel and etonogestrel have no affinity for the estrogen receptor, and hence have no estrogenic activity.
- These effects are mediated by its estrogenic activity.
- In addition to its anabolic and androgenic activity, nandrolone decanoate has low estrogenic activity (via its metabolite estradiol) and moderate progestogenic activity.
- Non-human animal studies have shown that exposure to environmental contaminants with estrogenic activity can accelerate the onset of puberty.
- The same study associated dextrorphan with estrogenic activity by using predictive modelling, before observing it in in vitro.
- 3-MC was found to elicit estrogenic activity by this mechanism, and by stimulation of the expression of some endogenous ER target genes.
- Androstenedione has been found to possess some estrogenic activity, similarly to other DHEA metabolites.
- A range of synthetic and natural substances that possess estrogenic activity have been identified in the environment and are referred to xenoestrogens.
- THG is a highly potent agonist of the androgen and progesterone receptors, around 10 times more potent than the comparison drugs nandrolone or trenbolone, but with no estrogenic activity.
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Enthält Übersetzungen von der TU Chemnitz sowie aus Mr Honey's Business Dictionary (nur Englisch/Deutsch).
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