Übersetzung für 'glypican' von Englisch nach Deutsch

glypican

Glypican {n}biochem.

• GPC3 is important in Sulf2-enhanced FGF signaling in vitro, so glypican-3 may mediate its own upregulation through Sulf2.
• Glypican-3 (GPC3) interacts with both Wnt and Frizzled to form a complex and triggers downstream signaling.
• She later expanded the research on glypican 4, showing that it is needed for the postsynaptic neurons to receive inputs.
• The protein has to be processed after being codified, and in its mature form it is composed by 626 amino acids, forming a proteoglycan rich in heparin sulfate which is anchored to the cell surface via covalent linkage to glycophosphatidylinositol (GPI), so we can define it as a glypican.
• The mutations causing this syndrome have been mapped to the glypican 4 ("GPC4") gene.

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• Glypicans can modify cell signaling pathways and contribute to cellular proliferation and tissue growth.