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Übersetzung für 'DMAPP' von Englisch nach Deutsch

dimethylallyl pyrophosphate <DMAPP>

Dimethylallylpyrophosphat {n} <Dimethyl-Allyl-PP, DMAPP>chem.

• Dimethylallylpyrophosphat {n} <Dimethyl-Allyl-PP, DMAPP> = dimethylallyl pyrophosphate <DMAPP>

• It catalyzes the addition of an isopentenyl group from dimethylallyl diphosphate (DMAPP) onto adenosine residue 37 of certain tRNA molecules.
• It is the first committed metabolite on that pathway on the route to IPP and DMAPP.
• IPP isomerase catalyzes the isomerization of IPP to DMAPP by an antarafacial transposition of hydrogen.
• The biosynthesis of andrographolide begins with the addition of IPP to DMAPP, which forms geranyl pyrophosphate.
• Upon forming IPP and DMAPP, the diterpene GGPP is formed by via head-to-tail addition by an Sn1 mechanism.

• In plants and bacteria, the non-mevalonate pathway (MEP pathway) uses pyruvate and glyceraldehyde 3-phosphate as substrates to produce IPP and DMAPP.
• The intermediate "c"AATrp is then prenylated with dimethylallyl pyrophosphate (DMAPP) by the enzyme CpaD to form the intermediate β-CPA.
• Following this NovQ catalyzes the electrophilic substitution of the phenyl ring with dimethylallyl pyrophosphate (DMAPP) otherwise known as prenylation.
• The biosynthetic route then continues with the activation of dimethylallyl pyrophosphate (DMAPP), produced via the mevalonate pathway, to form a carbo-cation via the cleavage of the diphosphates.
• In the mevalonate pathway DMAPP is synthesised from mevalonic acid. In contrast, DMAPP is synthesised from HMBPP in the MEP pathway.

• The other starting material is farnesyl pyrophosphate (FPP), which is produced from reaction between two isopentenyl pyrophosphate (IPP) and its isomer dimethylallyl pyrophosphate (DMAPP) with the help of FPP synthase.
• The same paper showed that the N5 alkylation occurred whether it was a DMAP or DMAPP substrate in the DMAPP specific UbiX from aspergillus niger (AnUbiX), therefore this step is independent of the beta phosphate present in DMAPP.
• The mevalonate pathway begins with acetyl-CoA and ends with the production of IPP and DMAPP.
• It may use ATP, ADP, or AMP as substrates and may use dimethylallyl pyrophosphate (DMAPP) or hydroxymethylbutenyl pyrophosphate (HMBPP) as prenyl donors.
• This compound is originated from mevalonic acid pathway which produce dimethylallyl diphosphate (DMAPP) from acetyl-CoA.

• The biosynthetic pathways to ergocryptine starts with the prenylation of L-tryptophan in an SN1 fashion with Dimethylallylpyrophosphate (DMAPP).