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Übersetzung für 'IL-6' von Englisch nach Deutsch

interleukin-6 <IL-6>

Interleukin-6 {n} <IL-6>biochem.med.

• Interleukin-6 {n} <IL-6> = interleukin-6 <IL-6>

• TNF-α and IL-6 concentrations are elevated in obesity. TNF and IL-6 are the most prominent cytokines predicting COVID-19 severity and death.
• Proinflammatory platelet microvesicles trigger constant cytokine secretion from neighboring fibroblast-like synoviocytes, most prominently Il-6 and Il-8.
• Low-grade chronic inflammation is characterized by a two- to threefold increase in the systemic concentrations of cytokines such as TNF-α, IL-6, and CRP.
• Interleukin 6 (acronym: IL-6) is a cytokine that is important for many aspects of cellular biology including immune responses, cell survival, apoptosis, as well as proliferation.
• Tocilizumab, an anti-IL-6 monoclonal antibody, was FDA approved for steroid-refractory CRS based on retrospective case study data.

• Metabolism of omega-3 polyunsaturated fatty acids produces docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which inhibits pro-inflammatory eicosanoids and cytokines (TNF-a, IL-1b and IL-6), decreasing both lymphocyte proliferation and reactive oxygen species.
• Sirolimus has complex effects on the immune system—while IL-12 goes up and IL-10 decreases, which suggests an immunostimulatory response, TNF and IL-6 are decreased, which suggests an immunosuppressive response.
• In the liver, its production is augmented by interleukin 6 (IL-6).
• If symptoms are due to an inflammatory syndrome, then anti-interleukin-6 (IL-6) therapy is recommended.
• Ferritin and IL-6 are considered to be possible immunological biomarkers for severe and fatal cases of COVID-19.

• People with fibromyalgia tend to have higher levels of inflammatory cytokines IL-6, and IL-8.
• A case-control study showed that 9 delirium cases showed higher expression of HLA-DR and CD68 (markers of microglial activation), IL-6 (cytokines pro-inflammatory and anti-inflammatory activities) and GFAP (marker of astrocyte activity) than age-matched controls; this supports a neuroinflammatory cause to delirium, but the conclusions are limited by methodological issues.
• This extra weight was not offset by the newer engines however, and the Il-4 proved to be slower than the earlier versions at only 404 km/h (251 mph).
• This so-called acute phase response occurs as a result of increasing concentrations of IL-6, which is produced by macrophages as well as adipocytes in response to a wide range of acute and chronic inflammatory conditions such as bacterial, viral, or fungal infections; rheumatic and other inflammatory diseases; malignancy; and tissue injury and necrosis.
• While studies looking at arachidonic acid supplementation in sedentary subjects have failed to find changes in resting inflammatory markers in doses up to 1,500 mg daily, strength-trained subjects may respond differently.

• The pathological mechanism is the result of an inflammatory cascade that is triggered by an as of yet undetermined cause resulting in dendritic cells in the vessel wall recruiting T cells and macrophages to form granulomatous infiltrates.
• Hepcidin decreases the amount of iron available for erythropoesis (red blood cell production).
• The lamina propria macrophages when under much stress release pro-inflammatory signals that may lead to increased probability of developing cancer.