Übersetzung für 'aneuploidy' von Englisch nach Deutsch

aneuploidy

Aneuploidie {f}biol.med.

• Brinkley is attempting to uncover the molecular basis of errors and defects in the nucleus and mitotic apparatus that cause aneuploidy.
• ... HeLa cells) caused aneuploidy. Whether aneuploidy alone is a sufficient driving cause during tumorigenesis or rather a mere consequence has been a matter of scientific debate.
• Partial aneuploidy can also occur as a result of unbalanced translocations during meiosis.
• When the spindle checkpoint misfunctions, this can lead to chromosome missegregation, aneuploidy and even tumorigenesis.
• In addition, there are pathological cases that result in aneuploidy and are almost always lethal.

• SibNIIRS has developed methods for breeding of new plant species using diploidization, introgressive hybridization, alloplasmia and aneuploidy.
• Stimulated by the finding of placental cells with abnormal chromosome complements (aneuploid cells) in her own pregnancy, she began to study the consequence of aneuploidy upon development in a mouse model.
• An aneugen is a substance that causes a daughter cell to have an abnormal number of chromosomes or aneuploidy. A substance's aneugenicity reflects its ability to induce aneuploidy.
• Exposure of spermatozoa to lifestyle, environmental and/or occupational hazards may increase the risk of aneuploidy.
• Chromosome segregation errors can lead to DNA damage and chromosomal aberrations such as aneuploidy which is linked to tumour development.

• Agents capable of causing aneuploidy are called aneugens.
• Somatic aneuploidy such as SNVs (single nucleotide variations) and CNVs (copy-number variations) have been particularly observed and linked to brain disfunctions when arising in prenatal brain development; anyway those somatic aneuploidy have been observed in rates of 1,3-40%, potentially increasing with age and for this reason they have been proposed as a mechanism to generate normal genetic diversity among neurons.
• Numerical CIN is a high rate of either gain or loss of whole chromosomes; causing aneuploidy.