Übersetzung für 'dacarbazine' von Englisch nach Deutsch

dacarbazine [C6H10N6O]

Dacarbazin {n}pharm.

• In 2015, (after a phase III study comparing trabectedin with dacarbazine A third "O"-methylated tyrosine is added and cyclized via Pictet-Spengler to yield the final product.
• A study has shown that fotemustine produces improved response rates and but does not increase survival (over dacarbazine in the treatment of disseminated cutaneous melanoma. ...
• Treatment is by chemotherapy with streptozocin, dacarbazine, doxorubicin or by 'watchful waiting' and surgical debulking via Whipple procedure and other resections of the gastrointestinal organs affected.
• Bayer continues to supply DTIC-Dome. There are also generic versions of dacarbazine available from APP, Bedford, Mayne Pharma (now Hospira) and Teva.
• Procarbazine works, in part, as an alkylating agent and methylates guanine at the O-6 position (much like dacarbazine also does).

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• In female human cancer patients that were treated with ABVD (adriamycin, bleomycin, vinblastine and dacarbazine) led to an increase in mean follicular density.
• Among the tyrosine kinase inhibitors used to treat DFSP-FS, imatinib (which is approved by the FDA for treating DFSP Chemotherapy regimens used to treat DFSP-FS include doxorubicin plus ifosfamide together or combined with an aromatase inhibitor and doxorubicin and ifosfamide combined with dacarbazine. ...
• Melanoma of the skin and eye, together with dacarbazine and interferon-alpha in combination chemotherapy.
• Malignant myoepitheliomas are excised and have been treated in the past with dacarbazine but are prone to both metastasis and re-occurrence.
• In the 152-patient trial, a combination of selumetinib and dacarbazine failed to improve progression-free survival compared with just the old drug alone.

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• Temozolomide is contraindicated in people with hypersensitivity to it or to the similar drug dacarbazine. The use of temozolomide is not recommended in people with severe myelosuppression.
• Given exceptionally poor patient outcomes in melanoma, a randomized double-blind trial was initiated using a standard drug (dacarbazine) with or without Genasense.
• The ECHELON-1 phase 3 trial compared brentuximab vedotin with bleomycin both in combination with adriamycin, vinblastine, dacarbazine (AVD) chemotherapy as a firstline treatment for advanced classical Hodgkin lymphoma.