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- Doppelstrang-RNA {f} <dsRNA, ds-RNA> = double-stranded RNA <dsRNA, ds-RNA>
- doppelsträngige RNA {f} <dsRNA> = double-stranded RNA <dsRNA>
- Doppelstrang-RNA-Virus {n} [ugs. auch {m}] <dsRNA-Virus> = double-stranded RNA virus <dsRNA virus>
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- MDA5 (melanoma differentiation-associated protein 5) is a RIG-I-like receptor dsRNA helicase enzyme that is encoded by the "IFIH1" gene in humans.
- 1975: Biological control of chestnut blight was demonstrated using hypovirulence, which was associated with dsRNA transmitted by hyphal anastomosis.
- Transcription of the dsRNA genome occurs inside the virion, and this is important so that the dsRNA is not exposed to the cytoplasm.
- It may be done by Decoy dsRNA, degradation, hiding of viral dsRNA, dimerization block, dephosphorylation of substrate or by a pseudosubstrate.
- RBPs contain various structural motifs, such as RNA recognition motif (RRM), dsRNA binding domain, zinc finger and others.
- (5) In type I systems Cas6e/Cas6f cleave at the junction of ssRNA and dsRNA formed by hairpin loops in the direct repeat.
- In addition, cyclin E dsRNA only diminished cyclin E RNA — a similar result was also shown using dsRNA corresponding to cyclin A which acts in S, G2 and M phases of the cell cycle.
- This however can be overcome by fabricating the single stranded RNA to double stranded RNA(dsRNA).
- Groups have found that the Interferon Signaling promotes the activation of a 2'-5'-oligoadenylate synthetase, sensitive to the presence of dsRNA longer than 15 base pairs.
- The protein encoded by this gene belongs to SID1 family of transmembrane dsRNA-gated channels. Family members transport dsRNA into cells and are required for systemic RNA interference.
- The carrot yellow leaf virus dsRNA genome is synthesized from the genomic ssRNA(+) within the host.
- Arboviruses containing dsRNA are placed in this genus. Some "Orbivirus" infect livestock with high rates of morbidity and mortality.
- Viruses in the family "Reoviridae" have genomes consisting of segmented, double-stranded RNA (dsRNA).
- Most viruses produce long dsRNA helices during transcription and replication.
- PKR (encoded in humans by the gene "EIF2AK2") activation is mainly dependent on the presence of double-stranded RNA during a viral infection. dsRNA causes PKR to form dimers, resulting in autophosphorylation and activation.
- Alternatively dsRNA can be supplied without genetic engineering.
- As the replicative dsRNA form is relatively stable, it can be found in comparatively high quantities in host tissues, and therefore is a likely subject of isolations (this is the reason why "Endornaviridae" often are classified as dsRNA viruses, in contrast to the official ssRNA(+) ICTV classification).
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Enthält Übersetzungen von der TU Chemnitz sowie aus Mr Honey's Business Dictionary (nur Englisch/Deutsch).
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