|NOUN || an eicosanoid | eicosanoids |
NOUN article.ind sg | pl
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- After inflammation has damaged tissue (when combatting bacterial infection for example) and pro-inflammatory eicosanoids have completed their function, healing proceeds in 4 phases.
- Inflammation is produced by eicosanoids and cytokines, which are released by injured or infected cells.
- The oxoeicosanoids are nonclassic eicosanoids, derived from arachidonic acid (AA).
- Nonclassic eicosanoids are biologically active signaling molecules made by oxygenation of twenty-carbon fatty acids other than the classic eicosanoids.
- The two-epi-Lx's as well as the two lx's are nonclassic eicosanoids that, like other members of the specialized pro-resolving mediators class of autocoids, form during and act to resolve inflammatory responses.
- Glucocorticoids stimulate production of lipocortin. In this way, synthesis of eicosanoids are inhibited.
- In addition to yielding anti-inflammatory eicosanoids, DGLA competes with AA for COX and lipoxygenase, inhibiting the production of AA's eicosanoids.
- Barry Sears (born June 6, 1947) Sears believed that the drug delivery principles could be applied to diet, in order to control the levels of eicosanoids to ultimately control inflammation.
- Upon downstream modification by cyclooxygenases or lipoxygenases, arachidonic acid is modified into active compounds called eicosanoids.
- Adenomyosis patients present with heavy menstrual bleeding due to the increase of endometrial tissue, greater degree of vascularization, atypical uterine contractions and increased levels of prostaglandins, estrogen and eicosanoids.
- Thromboxane is a member of the family of lipids known as eicosanoids.
- He is a leading authority on the biosynthesis of prostoglandins and eicosanoids.
- Cytosolic phospholipase A2-α acts on membrane phospholipids to release arachidonic acid a precursor in the synthesis of eicosanoids.
- Examples of biologically important fatty acids include the eicosanoids, derived primarily from arachidonic acid and eicosapentaenoic acid, that include prostaglandins, leukotrienes, and thromboxanes.
- (b) change cytokine biosynthesis; and (c) directly activate gene transcription. Of these, the action on eicosanoids is the best explored.
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