Übersetzung für 'eicosanoids' von Englisch nach Deutsch

eicosanoids

Eicosanoide {pl}biochem.

• After inflammation has damaged tissue (when combatting bacterial infection for example) and pro-inflammatory eicosanoids have completed their function, healing proceeds in 4 phases.
• Inflammation is produced by eicosanoids and cytokines, which are released by injured or infected cells.
• The oxoeicosanoids are nonclassic eicosanoids, derived from arachidonic acid (AA).
• Nonclassic eicosanoids are biologically active signaling molecules made by oxygenation of twenty-carbon fatty acids other than the classic eicosanoids.
• The two-epi-Lx's as well as the two lx's are nonclassic eicosanoids that, like other members of the specialized pro-resolving mediators class of autocoids, form during and act to resolve inflammatory responses.

  ---

• Glucocorticoids stimulate production of lipocortin. In this way, synthesis of eicosanoids are inhibited.
• In addition to yielding anti-inflammatory eicosanoids, DGLA competes with AA for COX and lipoxygenase, inhibiting the production of AA's eicosanoids.
• Barry Sears (born June 6, 1947) Sears believed that the drug delivery principles could be applied to diet, in order to control the levels of eicosanoids to ultimately control inflammation.
• Upon downstream modification by cyclooxygenases or lipoxygenases, arachidonic acid is modified into active compounds called eicosanoids.
• Adenomyosis patients present with heavy menstrual bleeding due to the increase of endometrial tissue, greater degree of vascularization, atypical uterine contractions and increased levels of prostaglandins, estrogen and eicosanoids.

  ---

• Thromboxane is a member of the family of lipids known as eicosanoids.
• He is a leading authority on the biosynthesis of prostoglandins and eicosanoids.
• Cytosolic phospholipase A2-α acts on membrane phospholipids to release arachidonic acid a precursor in the synthesis of eicosanoids.
• Examples of biologically important fatty acids include the eicosanoids, derived primarily from arachidonic acid and eicosapentaenoic acid, that include prostaglandins, leukotrienes, and thromboxanes.
• (b) change cytokine biosynthesis; and (c) directly activate gene transcription. Of these, the action on eicosanoids is the best explored.

  ---