Übersetzung für 'ifosfamide' von Englisch nach Deutsch

ifosfamide

Ifosfamid {n}chem.

• Both, evofosfamide and ifosfamide have been investigated in combination with doxorubicin in patients with advanced soft tissue sarcoma.
• Artificial cell enzyme therapy is also of interest for the activation of prodrugs such as ifosfamide in certain cancers.
• The disease can occur as a complication of cyclophosphamide, ifosfamide and radiation therapy.
• Biomarkers of exposure to antineoplastic drugs commonly include urinary platinum, methotrexate, urinary cyclophosphamide and ifosfamide, and urinary metabolite of 5-fluorouracil.
• Treatment is usually multimodal, involving surgery, chemotherapy and radiotherapy: The benefit of chemotherapy in synovial sarcoma to overall survival remains unclear, although a recent study has shown that survival of patients with advanced, poorly differentiated disease marginally improves with doxorubicin/ifosfamide treatment.

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• ... doxorubicin plus ifosfamide) is added to their surgical regimens.
• Cyclophosphamide and ifosfamide treatment results in the production of acrolein.
• Mesna, sold under the brand name Mesnex among others, is a medication used in those taking cyclophosphamide or ifosfamide to decrease the risk of bleeding from the bladder.
• Among the tyrosine kinase inhibitors used to treat DFSP-FS, imatinib (which is approved by the FDA for treating DFSP Chemotherapy regimens used to treat DFSP-FS include doxorubicin plus ifosfamide together or combined with an aromatase inhibitor and doxorubicin and ifosfamide combined with dacarbazine. ...
• Glufosfamide is, basically, a glycosidic conjugate between β-D-glucose and the active alkylating moiety of the well-known antineoplastic drug ifosfamide, so-called "isophosphoramide mustard".

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• It has been suggested that uterine adenosarcomas can respond to doxorubicin/ifosfamide and gemcitabine/docetaxel chemotherapy.
• In a phase-III clinical trial in about 800 newly diagnosed osteosarcoma patients, mifamurtide was combined with the chemotherapeutic agents doxorubicin and methotrexate, with or without cisplatin and ifosfamide.
• Chloroacetaldehyde is a metabolite of the antineoplastic ifosfamide and believed to be responsible for some of the toxicity observed with ifosfamide.
• Chemotherapy regimens include: doxorubicin/ifosfamide and doxorubicin combination/gemcitabine and docetaxel/trabectedin; pazopanib is the targeted therapy used in metastatic leiomyosarcoma as second line and is well tolerated.