Übersetzung für 'lagging strand' von Englisch nach Deutsch

lagging strand

nachfolgender Strang {m}biol.

diskontinuierlicher Strang {m}biol.

• These fragile sites are thought to form hairpin structures on the lagging strand during replication from single-stranded DNA base-pairing with itself in the trinucleotide repeat region.
• For eukaryotes specifically, the mechanism of DNA replication elongation between the leading and lagging strand differs.
• Two types of strands are created simultaneously during replication: the leading strand, which is synthesized continuously and grows towards the replication fork, and the lagging strand, which is made discontinuously in Okazaki fragments and grows away from the replication fork.
• Okazaki fragments are short sequences of DNA nucleotides (approximately 150 to 200 base pairs long in eukaryotes) which are synthesized discontinuously and later linked together by the enzyme DNA ligase to create the lagging strand during DNA replication.
• During DNA replication, the lagging strand of DNA binds in the central channel of dnaB, and the second DNA strand is excluded.

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• Most such primers are excised from newly synthesized lagging strand DNA by endonucleases of the family RNase H.
• DNA ligase then joins the fragmented strands together, completing the synthesis of the lagging strand.
• determining whether the tested helicase attaches to the DNA leading strand, or the DNA lagging strand.
• These two strands serve as the template for the leading and lagging strands, which will be created as DNA polymerase matches complementary nucleotides to the templates; the templates may be properly referred to as the leading strand template and the lagging strand template.
• This asymmetric conformation is capable of simultaneously replicating the leading and lagging strands, and the collection of factors that includes the replicative polymerases is generally referred to as a "holoenzyme".

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