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- Usually initial therapy is empirical. If sufficient reason to suspect influenza, one might consider oseltamivir. In case of legionellosis, erythromycin or fluoroquinolone.
- During the United States 2005–2006 influenza season, increasing incidence of drug resistance by strain H3N2 to amantadine and rimantadine led the CDC to recommend oseltamivir as a prophylactic drug, and the use of either oseltamivir or zanamivir as treatment.
- According to a research report published in June 2011, a new variant of swine flu had emerged in Asia with a genetic adaptation (a S247N neuraminidase mutation) giving some resistance to oseltamivir and zanamivir, but no significant reduction in sensitivity to peramivir.
- The NAIs oseltamivir and zanamivir were approved in the US and Europe for treatment and prevention of influenza A and B.
- Aminoshikimic acid is also an alternative to shikimic acid as a starting material for the synthesis of oseltamivir.
- Immunocompromised patients, more often than immunocompetent patients, hospitalized with pneumonia are at the highest risk of developing oseltamivir resistance during treatment.
- A 2011 meta-analysis of 15 studies found a pooled incidence rate for oseltamivir resistance of 2.6%.
- 85 percent of the world's star anise is grown in Guangxi. It is a major ingredient in the antiviral oseltamivir.
- In 2012, Jefferson was the lead author of another Cochrane review of this data which concluded that oseltamivir did not reduce the number of hospitalizations caused by influenza.
- Oseltamivir is used for patients 1 year and older. It is given as one dose, twice a day for the treatment of influenza.
- coli" to synthesize aminoshikimic acid, which is a promising starting material for the synthesis of antiinfluenza agent oseltamivir (brand name Tamiflu).
© dict.cc English-German dictionary 2024
Enthält Übersetzungen von der TU Chemnitz sowie aus Mr Honey's Business Dictionary (nur Englisch/Deutsch).
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