| NOUN | prothrombin | prothrombins |
| SYNO | factor II | prothrombin |
NOUN article.ind sg | pl
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Anwendungsbeispiele Englisch
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- Prothrombin time (PT) and its derived measures of prothrombin ratio (PR) and INR are measures of the extrinsic pathway of coagulation.
- Des-gamma carboxyprothrombin (DCP), also known as protein induced by vitamin K absence/antagonist-II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin.
- This prevents the formation of the active form of prothrombin and several other coagulant enzymes.
- Type II, known as dysprothrombinemia, includes a missense mutation at specific Xa factor cleavage sites and serine protease prothrombin regions.
- Alpha globulins include certain hormones, proteins that transport hormones, and other compounds, including prothrombin and HDL.
- Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein(a).
- Thrombokinase was the name coined by Paul Morawitz in 1904 to describe the substance that converted prothrombin to thrombin and caused blood to clot.
- During her graduate studies, Degen and her colleagues were the first to isolate and characterize complementary DNA (cDNA) coding for both bovine and human prothrombin.
- Prothrombin activator is a complex of a dozen blood coagulation factors that functions in catalyzing prothrombin into thrombin.
- Hyperprothrombinemia is a state of high of prothrombin levels in the blood which leads to hypercoagulability. An example of a genetic cause includes the mutation prothrombin G20210A.
- The primary antidote to brodifacoum poisoning is immediate administration of vitamin K1 (dosage for humans: initially slow intravenous injections of 10–25 mg repeated at 3–6 hours until normalisation of the prothrombin time; then 10 mg orally four times daily as a "maintenance dose").
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