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 Übersetzung für 'thiazolidinediones' von Englisch nach Deutsch
NOUN   thiazolidinedione | thiazolidinediones
pharm.
thiazolidinediones
Glitazone {pl}
pharm.
thiazolidinediones
Thiazolidindione {pl}
pharm.
thiazolidinediones
Insulin-Sensitizer {pl}
3 Übersetzungen
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Übersetzung für 'thiazolidinediones' von Englisch nach Deutsch

thiazolidinediones
Glitazone {pl}pharm.

Thiazolidindione {pl}pharm.

Insulin-Sensitizer {pl}pharm.
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Anwendungsbeispiele Englisch
  • PPARγ (gamma) is the main target of the drug class of thiazolidinediones (TZDs), used in diabetes mellitus and other diseases that feature insulin resistance.
  • The triacylglycerol reducing effect of fibrates and thiazolidinediones, strong and selective agonists of PPARalpha and PPARgamma, is partially caused by inhibition of SREBP-1 activation via up-regulation of Insig.
  • Many insulin sensitizing drugs (namely, the thiazolidinediones) used in the treatment of diabetes activate PPARG as a means to lower serum glucose without increasing pancreatic insulin secretion.
  • Exenatide is used to treat type 2 diabetes mellitus as an add-on to metformin, a biguanide, or a combination of metformin and a sulfonylurea, or thiazolidinediones such as pioglitazone.
  • Thiazolidines functionalized with carbonyls at the 2 and 4 positions, the thiazolidinediones, are drugs used in the treatment of diabetes mellitus type 2.

  • Pregabalin may enhance the fluid-retaining effect of certain anti-diabetic agents (thiazolidinediones).
  • Both metformin and thiazolidinediones improve insulin sensitivity.
  • Patients with MODY less often suffer from obesity and insulin resistance than those with ordinary type 2 diabetes (for whom insulin sensitizers like metformin or the thiazolidinediones are often preferred over the sulfonylureas).
  • Ciglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones.
  • Pioglitazone cannot be used in patients with a known hypersensitivity to pioglitazone, other thiazolidinediones or any of components of its pharmaceutical forms.

  • Evidence was emerging in 2008 that vitamin E with thiazolidinediones is effective in the treatment of non-alcoholic steatohepatitis due to their combined antioxidant and insulin sensitizing effects, producing histological improvements in steatosis severity.
  • Anti-diabetic medications such as insulin, metformin, or thiazolidinediones are used for insulin-resistance or high glucose levels, or statins or fibrates are used for hyperlipidemia.
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Enthält Übersetzungen von der TU Chemnitz sowie aus Mr Honey's Business Dictionary (nur Englisch/Deutsch).
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