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Übersetzung für 'Anaphase' von Englisch nach Deutsch

anaphase

Anaphase {f}biol.

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anaphase inhibitor

Anaphase-Inhibitor {m}biochem.biol.

• Anaphase {f} = anaphase
• Anaphase-Inhibitor {m} = anaphase inhibitor

• RACGAP1 also interacts with PRC1 to stabilize and maintain the central spindle as anaphase proceeds.
• Anaphase starts when the anaphase promoting complex marks an inhibitory chaperone called securin for destruction by ubiquitylating it.
• The spindle assembly checkpoint inhibits progression of mitosis from metaphase to anaphase until all sister chromatid pairs are bioriented.
• Securin is a protein involved in control of the metaphase-anaphase transition and anaphase onset.
• Separase, also known as separin, is a cysteine protease responsible for triggering anaphase by hydrolysing cohesin, which is the protein responsible for binding sister chromatids during the early stage of anaphase.

• The difference between the two constrictions can be noticed during anaphase, as chromosomes can only bend at the site of primary constriction.
• This prevents premature progression into anaphase by inhibiting the anaphase-promoting complex until all kinetochores are attached and all the chromosomes aligned.
• Once activated, the spindle checkpoint blocks anaphase entry by inhibiting the anaphase-promoting complex via regulation of the activity of mitotic checkpoint complex.
• KIF4B and the closely related protein KIF4A are essential for regulating anaphase spindle dynamics during mitosis.
• The anaphase- promoting complex or cyclosome (APC/C) is a highly specific ubiquitin protein ligase responsible for triggering events of late mitosis.

• MPF is disassembled when anaphase-promoting complex (APC) polyubiquitinates cyclin B, marking it for degradation in a negative feedback loop.
• Only after all chromosomes have become aligned at the "metaphase plate", when every kinetochore is properly attached to a bundle of microtubules, does the cell enter anaphase.
• Historically, it has been thought that anaphase and telophase are events that occur passively after satisfaction of the spindle-assembly checkpoint (SAC) that defines the metaphase-anaphase transition.
• Prolonged activation of the spindle assembly checkpoint inhibits the anaphase promoting complex.
• The site of cell division is determined before anaphase.