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Übersetzung für 'Fab-Fragment' von Englisch nach Deutsch

fragment antigen-binding <Fab fragment>

Fab-Fragment {n}biol.

• Fab-Fragment {n} = fragment antigen-binding <Fab fragment>

• The CYT domain consist of an ellipsoidal antiparallel β-sandwich with dimensions of 30 x 36 x 47 Å and a topology resembling the variable heavy chain of the antibody Fab fragment with a five-stranded inner β-sheet and a six-stranded outer β-sheet .
• It is a fusion protein of a human tumor-associated 5T4 antigen monoclonal IgG1 Fab fragment with an enterotoxin ('mafenatox') of "Staphylococcus aureus".
• The variable regions of the heavy and light chains can be fused together to form a single-chain variable fragment (scFv), which is only half the size of the Fab fragment, yet retains the original specificity of the parent immunoglobulin.
• Certolizumab pegol is a monoclonal antibody directed against tumor necrosis factor alpha. More precisely, it is a PEGylated Fab' fragment of a humanized TNF inhibitor monoclonal antibody.
• For example, it has been reported that Taurine significantly increases the yield of in vitro refolding for Fab fragment antibodies.

• This consists of an upstream (pre viral inactivation) suite for the fractionation of IgG from whole serum or plasma and a downstream (post viral inactivation) suite to conduct further processing and formulation of the Fab fragment.
• It was the Fab' fragment of a mouse monoclonal antibody labelled with the radioisotope indium-111 for the diagnosis of thromboembolism, but was withdrawn during clinical trials.
• Citatuzumab bogatox (VB6-845) is a monoclonal antibody Fab fragment fused with bouganin, a ribosome inactivating protein from the plant "Bougainvillea spectabilis".
• Ovine polyclonal anti-digitoxin Fab fragment antibody (DigiTAb; Therapeutic Antibodies Inc.) can be used to treat "T.
• Structurally Fab fragments consist of two sets of variable and constant components, which create two polypetide chains.