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 Übersetzung für 'H2-receptor' von Englisch nach Deutsch
pharm.
H2-receptor antagonists
H2-Rezeptorantagonisten {pl}
1 Übersetzung
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Übersetzung für 'H2-receptor' von Englisch nach Deutsch

H2-receptor antagonists
H2-Rezeptorantagonisten {pl}pharm.
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Anwendungsbeispiele Englisch
  • Vasodilation and increased permeability of capillaries are a result of both H1 and H2 receptor types.
  • Proton-pump inhibitors (PPIs), such as omeprazole, are the most effective, followed by H2 receptor blockers, such as ranitidine.
  • The first QSAR study of brain–blood distribution was conducted in 1988, this study reported the in vivo values in rats for a large number of H2 receptor histamine agonists.
  • Activation of the H1 subtype receptor causes contraction of smooth muscle, whereas activation of the H2 receptor stimulates gastric secretion.
  • Nizatidine is a histamine H2 receptor antagonist that inhibits stomach acid production, and is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.

  • Ranitidine and other histamine H2 receptor antagonists may increase the risk of pneumonia in hospitalised patients.
  • While emergency surgery was once the only treatment, combination therapies including enteral feeding with powerful antacids such as H2-receptor antagonists or, more recently, proton pump inhibitors such as omeprazole have made Curling's ulcer a rare complication.
  • Galactorrhea is also a side effect associated with the use of the second-generation H2 receptor antagonist cimetidine (Tagamet).
  • H2 receptor antagonists, such as famotidine and nizatidine, in use for treatment of peptic ulcers, are known for causing blood dyscrasia – leading to bone marrow failure in 1 out of 50,000 patients.
  • H2-receptor antagonists are sometimes used in addition to H1-antagonists to treat urticaria, but there is limited evidence for their efficacy.

  • Famotidine, sold under the brand name Pepcid among others, is a histamine H2 receptor antagonist medication that decreases stomach acid production.
  • Low levels of magnesium can be found in people on PPI therapy and these can be reversed when they are switched to H2-receptor antagonist medications.
  • Treatment can include proton-pump inhibitors and H2 receptor antagonists used for digestive symptoms such as acid reflux.
  • Antacids do not directly inhibit acid secretion, and thus are distinct from acid-reducing drugs like H2-receptor antagonists or proton pump inhibitors.
  • Proton pump inhibitors (such as omeprazole and lansoprazole) and histamine H2-receptor antagonists (such as famotidine and ranitidine) are used to slow acid secretion.

  • Cimetidine was the first of a new class of drugs, the H2-receptor antagonists.
  • The H2-receptor antagonist cimetidine causes an increase in the plasma concentration of metformin by reducing clearance of metformin by the kidneys; both metformin and cimetidine are cleared from the body by tubular secretion, and both, particularly the cationic (positively charged) form of cimetidine, may compete for the same transport mechanism.
  • H2 receptors are positively coupled to adenylate cyclase via Gs alpha subunit.
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