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Übersetzung für 'JAK-STAT' von Englisch nach Deutsch

JAK-STAT signaling pathway

JAK-STAT-Signalweg {m}biol.

• JAK-STAT-Signalweg {m} = JAK-STAT signaling pathway

• In addition to the JAK-STAT pathway, IFNs can activate several other signaling cascades.
• Beginning in the 2000s, the incorporation of biopharmaceuticals (which include inhibitors of TNF-alpha, certain interleukins, and the JAK-STAT signaling pathway) into standards of care is one of the paramount developments in modern rheumatology.
• This local action of FGF proteins is classified as paracrine signalling, most commonly through the JAK-STAT signalling pathway or the receptor tyrosine kinase (RTK) pathway.
• Crocin through the PI3K/AKT/mTOR, MAPK, VEGF, Wnt/β-catenin, and JAK-STAT suppression has antiproliferative properties.
• The proinflammatory cytokines, interleukin-6 and leukemia inhibitory factor, can also induce peripherin expression through the JAK-STAT signaling pathway.

• The initial reaction of infected cells is to produce interferon, a cytokine that raises many defenses against viral infection through the innate immune system by augmenting the production of a large group of proteins mediated by the JAK-STAT pathway.
• Furthermore, one can integrate the accumulated knowledge about biochemical pathways (like the JAK-STAT signaling pathway) using this approach.
• The pleiotropic effects of IL-2 are enabled due to the fact that IL-2 signal can be transduced via 3 different signaling pathways; JAK-STAT, PI3K/Akt/mTOR and MAPK/ERK pathway.
• After STATs are made by protein biosynthesis, they have non-protein molecules attached to them, called post-translational modifications.