Übersetzung für 'N-acetylmuramic' von Englisch nach Deutsch

N-acetylmuramic acid

N-Acetylmuraminsäure {f}biochem.

• Peptidoglycan is the main component of bacterial cell wall and is a polymer of β(1-4)-linked "N"-acetylglucosamine (GlcNAc) and "N"-acetylmuramic acid (MurNAc) with MurNAc-attached short peptides, typically composed of alternating L and D amino acids, that cross-link the adjacent polysaccharide chains.
• Muramyl dipeptide is constituent of both Gram-positive and Gram-negative bacteria composed of N-acetylmuramic acid linked by its lactic acid moiety to the N-terminus of an L-alanine D-isoglutamine dipeptide.
• This binding of vancomycin to the D-Ala-D-Ala prevents cell wall synthesis of the long polymers of "N"-acetylmuramic acid (NAM) and "N"-acetylglucosamine (NAG) that form the backbone strands of the bacterial cell wall, and it prevents the backbone polymers that do manage to form from cross-linking with each other.
• The cell wall of some gram-positive bacteria can be completely dissolved by lysozymes which attacks the bonds between N-acetylmuramic acid and N-acetylglucosamine.
• It is part of a biopolymer in the bacterial cell wall, which is built from alternating units of GlcNAc and "N"-acetylmuramic acid (MurNAc), cross-linked with oligopeptides at the lactic acid residue of MurNAc.

• UDP-N-acetylenolpyruvylglucosamine Reductase (MurB) is an enzyme that catalyzes the NADPH-dependent reduction of enolpyruvyl-UDP-N-acetylglucosamine (substrate) to the corresponding D-lactyl compound UDP-N-acetylmuramic acid (product).
• The bacterial cell wall differs from that of all other organisms by the presence of peptidoglycan (poly-"N"-acetylglucosamine and "N"-acetylmuramic acid), which is located immediately outside of the cytoplasmic membrane.
• Lipid II is then transported across the membrane by a flippase, to expose the disaccharide-pentapeptide monomer, which is the pentapeptide stem consisting of L-Ala-γ-D-Glu-m-DAP-D-Ala-D-Ala between GlcNAc and "N"-acetylmuramic acid (MurNAc), for polymerization and cross-linking into peptidoglycan.
• During the last stages of peptidoglycan biosynthesis, uridine diphosphate-"N"-acetylmuramic acid pentapeptide (UDP-MurNAc) is formed in which the fourth and fifth amino acids are both D-alanyl-D-alanine.
• These include (1) N-glycosylation of N-acetyl-muramic acid, (2) O-acetylation of N-acetylmuramic acid and (3) N-deacetylation of N-acetyl-glucosamine.

• "N"-Acetylmuramic acid (NAM or MurNAc) is an organic compound with the chemical formula [...].