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 Übersetzung für 'NMDA antagonists' von Englisch nach Deutsch
pharm.
N-methyl-D-aspartate antagonists <NMDA antagonists>
N-Methyl-D-Aspartat-Antagonisten {pl} <NMDA-Antagonisten>
Teiltreffer
biochem.
NMDA receptor <NMDAR>
NMDA-Rezeptor {m}
antagonistsAntagonisten {pl}
antagonistsWidersacher {pl}
22
pharm.
hormone antagonists
Hormonantagonisten {pl}
pharm.
receptor antagonists
Rezeptorantagonisten {pl}
pharm.
dopamine antagonists
Dopamin-Antagonisten {pl}
pharm.
calcium antagonists
Calciumantagonisten {pl}
pharm.
H2-receptor antagonists
H2-Rezeptorantagonisten {pl}
chem.
folic acid antagonists
Folsäureantagonisten {pl}
pharm.
angiotensin II receptor antagonists
Angiotensin-II-Rezeptor-Antagonisten {pl}
11 Übersetzungen
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Anwendungsbeispiele Englisch
  • Alterations in production of endogenous NMDA antagonists such as agmatine and kynurenic acid have been shown in schizophrenia.
  • Siramesine has been shown to produce an enhanced antidepressant effect when co-administered with NMDA antagonists.
  • Afterglow may also occur after the usage of dissociative drugs, such as the NMDA antagonists, DXM, ketamine and PCP.
  • Conversely, coadministration of NMDA-antagonists with alpha-2 adrenergic antagonists, like yohimbine, could theoretically potentiate NAN.
  • when first-line treatment options fail, NMDA antagonists such as amantadine or memantine may be used.

  • The use of D-methionine to protect against hearing loss induced by drugs like cisplatin and aminoglycosides is preliminarily supported by animal studies. NMDA antagonists are also shown to limit aminoglycosides-induced ototoxicity.
  • This hypothesis was corroborated by evidence that NMDA antagonists have antidepressant effects in rodents.
  • Cytotoxicity can be blocked by noncompetitive NMDA antagonists, such as dextrorphan and MK-801.
  • Gavestinel is an NMDA antagonist, binding selectively to the glycine site on the NMDA receptor complex, rather than the glutamate site many NMDA antagonists bind to.
  • In animal models, NMDA antagonists increase glutamate release in the prefrontal cortex.

  • Researchers have examined many different NMDA antagonists and their therapeutic efficacy, none of which have concluded to be both safe and effective.
  • In 1989, John Olney discovered that neuronal vacuolation and other cytotoxic changes ("lesions") occurred in brains of rats administered NMDA antagonists, including PCP and ketamine.
  • Dextromethorphan (the stereoisomer of levomethorphan, a semi-synthetic opioid agonist) and its metabolite dextrorphan have no opioid analgesic effect at all despite their structural similarity to other opioids; instead they are potent NMDA antagonists and sigma 1 and 2-receptor agonists and are used in many over-the-counter cough suppressants.
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