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 ⇄Suchrichtung
 Übersetzung für 'NMDA' von Englisch nach Deutsch
biochem.
NMDA receptor <NMDAR>
NMDA-Rezeptor {m}
pharm.
N-methyl-D-aspartate antagonists <NMDA antagonists>
N-Methyl-D-Aspartat-Antagonisten {pl} <NMDA-Antagonisten>
2 Übersetzungen
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  • NMDA-Rezeptor {m} = NMDA receptor <NMDAR>
  • N-Methyl-D-Aspartat-Antagonisten {pl} <NMDA-Antagonisten> = N-methyl-D-aspartate antagonists <NMDA antagonists>
  • N-Methyl-D-Aspartat-Rezeptoren {pl} <NMDA-R> = N-methyl-D-aspartate-receptors <NMDARs>
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Anwendungsbeispiele Englisch
  • 0715) is an NMDA antagonist drug candidate which selectively inhibits the NR2B (GLUN2B) subtype NMDA receptor at submicromolar concentrations.
  • Tetrazolylglycine (Tet-Gly, LY-285,265) is a potent and selective NMDA receptor agonist, stimulating the NMDA receptor with higher potency than either glutamate or NMDA.
  • Alterations in production of endogenous NMDA antagonists such as agmatine and kynurenic acid have been shown in schizophrenia.
  • In 1988, NMDA led the market's recovery by negotiating a long-term lease with the city, effectively eliminating the threat of demolition. In 1989, the NMDA assumed daily operations of the market.
  • Felbamate has been proposed to have a unique dual mechanism of action as a positive modulator of GABAA receptors and as a blocker of NMDA receptors, particularly isoforms containing the NR2B subunit.

  • The function of NMDA receptors varies according to the subregion of the hippocampus.
  • 5,7-Dichlorokynurenic acid (DCKA) is a selective NMDA receptor antagonist acting at the glycine site of the NMDA receptor complex.
  • Similar to many other solvents such as 1,1,1-trichloroethane and some alkylbenzenes, toluene has been shown to act as a non-competitive NMDA receptor antagonist and GABAA receptor positive allosteric modulator.
  • It is a selective NMDA receptor antagonist that competitively inhibits the ligand (glutamate) binding site of NMDA receptors.
  • Structural changes associated with addiction can be inhibited by NMDA receptor antagonists which block the activity of NMDA receptors.

  • Phencyclidine is an NMDA receptor antagonist that blocks the activity of the NMDA receptor to cause anaesthesia and analgesia without causing cardiorespiratory depression.
  • Rapastinel was originally invented by Joseph Moskal, the co-founder of Naurex, via structural modification of B6B21, a monoclonal antibody that similarly binds to and modulates the NMDA receptor.
  • Gavestinel is an NMDA antagonist, binding selectively to the glycine site on the NMDA receptor complex, rather than the glutamate site many NMDA antagonists bind to.
  • NMDA receptors are a crucial part of the development of the central nervous system.
  • Dextromethorphan has been noted to slow the development of and reverse tolerance to opioids, as well as to exert additional analgesia by acting upon NMDA receptors, as does ketamine.

  • In 1989, John Olney discovered that neuronal vacuolation and other cytotoxic changes ("lesions") occurred in brains of rats administered NMDA antagonists, including PCP and ketamine.
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Enthält Übersetzungen von der TU Chemnitz sowie aus Mr Honey's Business Dictionary (nur Englisch/Deutsch).
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