Übersetzung für 'NMDARs' von Englisch nach Deutsch

N-methyl-D-aspartate-receptors <NMDARs>

N-Methyl-D-Aspartat-Rezeptoren {pl} <NMDA-R>pharm.

• STEP dephosphorylation of GluN2B and GluA2 leads to the internalization of NMDARs (GluN1/GluN2B) and AMPARs (GluA1/GluA2).
• Other functions of this gliotransmitter include synchronous depolarization, increasing the frequency of postsynaptic currents, and also increasing the likelihood of release and frequency of AMPA-receptor-dependent postsynaptic currents NMDARs are controlled by a voltage-gated channel receptor that is blocked by magnesium.
• In addition, alcohol also inhibits the activity of "N"-methyl-D-aspartate receptors (NMDARs).
• For example, group I mGluRs are known to increase the activity of "N"-methyl-"D"-aspartate receptors (NMDARs), mGluRs tend to protect neurons from excitotoxicity, and in neurotoxicity and neuroprotection.
• As a result of this stabilization, both EphB2 forward signaling and ephrin-B3 reverse signaling has been found to induce LTP via NMDARs.

• It is sometimes used in conjunction with the calcium chelator BAPTA to determine whether NMDARs are required for a particular cellular process.
• oscillations involve glutamate release and activation of NMDARs (glutamate receptors).
• Hilmar Bading and his co-workers uncovered the importance of a death signaling complex consisting of extrasynaptic NMDA receptors (NMDARs) and TRPM4 for excitotoxicity and identified a class of neuroprotective small molecules (known as NMDAR/TRPM4 interaction interface inhibitors or short ‚interface inhibitors‘) that disrupt the NMDAR/TRPM4 complex and protect against cell death in mouse models of stroke and retinal ganglion cell degeneration.
• Extracellular Ca2+ can enter the spine through NMDA receptors (NMDARs) and voltage gated Ca2+ channels (VGCCs).
• Autapses have been used to simulate "same cell" conditions to help researchers make quantitative comparisons, such as studying how "N"-methyl-D-aspartate receptor (NMDAR) antagonists affect synaptic versus extrasynaptic NMDARs.

• It has been suggested that a reduction in NMDAR-dependent LTD may be due to changes not only in postsynaptic AMPARs but also in NMDARs, and these changes are perhaps present in early and mild forms of Alzheimer-type dementia.
• Hebian plasticity is believed to involve N-methyl-d-aspartate receptors (NMDARs) and are located on postsynaptic neurons in the lateral amygdala.
• Cochlear NMDARs are the target of intense research to find pharmacological solutions to treat tinnitus.