Übersetzung für 'P450' von Englisch nach Deutsch
cytochrome P450 <CYP, P450, CYP450>
Cytochrom P450 {n} <CYP, P450, CYP450>
cytochrome P450 <CYP, P450, CYP450>
Zytochrom P450 {n} <CYP, P450, CYP450>
cytochromes P450
Cytochrome P450 {pl} <CYP>
3 Übersetzungen
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  • Cytochrom P450 {n} <CYP, P450, CYP450> = cytochrome P450 <CYP, P450, CYP450>
  • Cytochrome P450 {pl} <CYP> = cytochromes P450
  • Zytochrom P450 {n} <CYP, P450, CYP450> = cytochrome P450 <CYP, P450, CYP450>
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Anwendungsbeispiele Englisch
  • After intravenous infusion it is extensively metabolised in the liver by cytochrome p450.
  • Through Wagner–Meerwein rearrangement reaction, the propyl intermediate is converted into Calanolide A, B, or C with the help of p450 monooxygenase enzyme.
  • This enzyme participates in metabolism of xenobiotics by cytochrome p450.
  • In the case of the protease inhibitor based regimens, ritonavir is used at low doses to inhibit cytochrome p450 enzymes and "boost" the levels of other protease inhibitors, rather than for its direct antiviral effect.
  • 25-Hydroxyvitamin D 1-alpha-hydroxylase (VD 1A hydroxylase) also known as calcidiol 1-monooxygenase or cytochrome p450 27B1 (CYP27B1) or simply 1-alpha-hydroxylase is a cytochrome P450 enzyme that in humans is encoded by the "CYP27B1" gene.

  • Artificial cells encapsulating the cytochrome p450 enzyme which converts this prodrug into the active drug can be tailored to accumulate in the pancreatic carcinoma or implanting the artificial cells close to the tumor site.
  • An ecdysteroid is a type of steroid hormones in insects that are derived from enzymatic modification of cholesterol by p450 enzymes.
  • NOSs can be dimeric, calmodulin-dependent or calmodulin-containing cytochrome p450-like hemoprotein that combines reductase and oxygenase catalytic domains in one dimer, bear both flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), and carry out a 5`-electron oxidation of non-aromatic amino acid arginine with the aid of tetrahydrobiopterin.
  • Like Δ9-THC and Δ8-THC, HHC is processed by cytochrome p450 (CYP3A4, CYP2C9 and CYP2C19) to a series of oxygenated derivatives, some of which maintain activity.
  • In a pathway that parallels the metabolism of the THC family of cannabinoids, following ingestion HHC undergoes hepatic metabolism by cytochrome p450 (predominantly the CYP3A4 isozyme, with some contribution from CYP2C9 and CYP2C19) to a multitude of oxygenated derivatives, including 8-OH-HHC and 11-OH-HHC.

  • The Dod-13 gene in the worm "Caenorhabditis elegans" encoding a cytochrome p450 enzyme, which have steroid hydroxylase activity, with the CYP Symbol CYP35B1 (Cytochrome P450, family 35, member B1).
  • esculenta" mycelia is able to bind to and inhibit the effects of furanocoumarins, chemicals found in grapefruit that inhibit human cytochrome p450 enzymes and are responsible for the "grapefruit/drug" interaction phenomenon.
  • The cytochrome p450 system is found in nearly all life forms and is responsible for processing pheromones and steroids and also metabolizing insecticides, drugs, mutagens, and carcinogens.
  • The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal dominant form of nonsyndromic optic nerve aplasia (ONA).
  • BLVRB binds to human heme oxygenase-1 (hHO-1) in conjunction with cytochrome p450 reductase to catalyzes the NADPH-cytochrome P450 reductase-dependent oxidation of heme to biliverdin, CO, and free iron.

  • It only has variable activity in-vitro and it has strong effects on the therapeutic levels of other antimicrobials used by inducing cytochrome p450 pathways.
  • They are used in human drug interaction studies in which the ability of a study drug to inhibit or induce cytochrome p450 enzymes is studied.
  • Additionally, three cytochrome P450s ("Pl-p450-1, Pl-p450-2 and Pl-p450-3") are involved in the final steps of the pleuromutilin biosynthetic pathway.
  • The existence/prevalence of anti-Cry mutations (for example mutations in ABCA2) and other insecticide resistance mutations (for example, the cytochrome p450 mutation CYP337B3) is unassessed [...] and such information will be needed to monitor changes in resistance across populations over time.
  • The following alterations were discovered: Ethoxyresorufin-O-deethylase activity was elevated 40-fold over controls; total cytochrome p450 content doubled and exhibited a 2 nanometer blue shift in the Soret maximum for the reduced hemoprotein-CO complex.

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    Enthält Übersetzungen von der TU Chemnitz sowie aus Mr Honey's Business Dictionary (nur Englisch/Deutsch).
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