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 Übersetzung für 'Ubiquitin-Ligase' von Englisch nach Deutsch
NOUN   a ubiquitin ligase | ubiquitin ligases
biochem.
ubiquitin ligase
Ubiquitinligase {f}
biochem.
ubiquitin ligase
Ubiquitin-Ligase {f}
2 Übersetzungen
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Übersetzung für 'Ubiquitin-Ligase' von Englisch nach Deutsch

ubiquitin ligase
Ubiquitinligase {f}biochem.

Ubiquitin-Ligase {f}biochem.
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  • Ubiquitin-Ligase {f} = ubiquitin ligase
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Anwendungsbeispiele Englisch
  • This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription.
  • The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis.
  • IRF3 degradation is dependent on the presence of NSP1 and the integrity of the N-terminal zinc-binding domain, coupled with the regulated stability of IRF3 and NSP1 by the proteasome, collectively support the hypothesis that NSP1 is an E3 ubiquitin ligase.
  • FBXL3 is a member of the F-box protein family, which constitutes one of the four subunits in the SCF ubiquitin ligase complex.
  • PCAF has separate acetyltransferase and E3 ubiquitin ligase domains as well as a bromodomain for interaction with other proteins.

  • The phosphorylated motif is recognized by β-TrCP, a ubiquitin ligase that targets plakoglobin 26S proteasome-dependent degradation.
  • Once the receptor and PA returns to the lipid raft, E3 ubiquitin ligase Cb1 ubiquitinates the cytoplasmic tail of the receptor, signaling the receptor and associated toxin proteins for endocytosis.
  • Their nuclear functions are not fully understood, but it was shown that all four mammalian arrestin subtypes remove some of their partners, such as protein kinase JNK3 or the ubiquitin ligase Mdm2, from the nucleus.
  • Meanwhile, sT has been shown to induce cell proliferation through hyper-phosphorylation of the translation initiator 4EBP1 as well as inhibition of a ubiquitin ligase complex responsible for degradation of cellular proliferation signals.
  • The protein contains a RING motif with E3 Ubiquitin Ligase activity.

  • COX-2 up-regulation has also been linked to the phosphorylation and activation of the E3 ubiquitin ligase HDM2, a protein that mediates p53 ligation and tagged destruction, through ubiquitination.
  • Anaphase-promoting complex (also called the cyclosome or APC/C) is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the 26S proteasome.
  • Some ligases associate with biological membranes as peripheral membrane proteins or anchored through a single transmembrane helix, for example certain ubiquitin ligase related proteins.
  • NHLRC1 encodes the protein malin, an E3 ubiquitin ligase, that regulates the amount of laforin.
  • There are two known substrates for this ubiquitin ligases; p53 and the MRN complex.

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    Enthält Übersetzungen von der TU Chemnitz sowie aus Mr Honey's Business Dictionary (nur Englisch/Deutsch).
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