Übersetzung für 'cytolytic' von Englisch nach Deutsch

cytolytic {adj}

zytolytisch

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cytolytic T cell <Tc>

T-Killerzelle {f} [veraltet] [cytotoxische T-Zelle] <Tc-Zelle>biol.

• The only so far reported ligand of KIR2DL4 is the non-classical HLA class 1 gene HLA-G, leading to the inhibition of the cytolytic NK cell function.
• The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity.
• Natural killer cells can use NKG2D receptors to detect senescent cells, and kill those cells using perforin pore-forming cytolytic protein.
• Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion, survival and cytolytic activity.
• In both humans and mice IELs express higher levels of CD103, activation marker CD69, granzyme B and perforin cytolytic granules. CD25 expression is lower in comparison with effector memory T cells.

• The term "Cytolysin" or "Cytolytic toxin" was first introduced by Alan Bernheimer to describe membrane damaging toxins (MDTs) that have cytolytic effects to cells.
• The proteolytic cleavage of C5 is the only known enzymatic event in assembly of the cytolytic membrane attack complex of complement.
• The venom of this species of stonefish is a tetrameric glycoprotein with cardiovascular and cytolytic effects.
• Coxsackie A virus (CAV) is a cytolytic Coxsackievirus of the "Picornaviridae" family, an enterovirus (a group containing the polioviruses, coxsackieviruses, and echoviruses).
• As a postdoctoral fellow, she explored the responses of helper T cell responses to influenza and mapped critical domains of class I Major Histocompatibility Complex molecules necessary for presenting viral peptides to cytolytic T cells.

• Stonustoxin (SNTX) is an extremely potent cytolytic toxin of the perforin-like superfamily.
• High CYT within colorectal cancer is associated with improved survival, likely due to increased immunity and cytolytic activity of T cells and M1 macrophages.
• Isatuximab is indicated as a CD38-directed cytolytic antibody. By inhibiting the enzymatic activity of CD38.
• T-bet activation is required for both interferon gamma and cytolytic potential.
• Cupiennins are a group of small cytolytic peptides from the venom of the wandering spider "Cupiennius salei".

• NK cells are a key part of innate immunity, mainly involved in the early cytolytic defense against infections and tumors.
• 3-Alkylpyridinium monomers and compounds are considered to have cytolytic activity but at present there are no such reports found that support this mechanism.
• Subtype α2 increases the expression of HLA-I molecules, which correlates with IFN-α-mediated activation of memory CD8 cells and increased cytolytic action against virally infected cells and tumor cells (via cytotoxic CD8 cells).
• Listeriolysin O is a non-enzymatic, cytolytic, thiol-activated, cholesterol-dependent cytolysin; hence, it is activated by reducing agents and inhibited by oxidizing agents.