Übersetzung für 'eflornithine' von Englisch nach Deutsch
NOUN   eflornithine | eflornithines
eflornithine [C6H12F2N2O2]
Eflornithin {n}
1 Übersetzung
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Übersetzung für 'eflornithine' von Englisch nach Deutsch

eflornithine [C6H12F2N2O2]
Eflornithin {n}pharm.
Anwendungsbeispiele Englisch
  • For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment.
  • For example, it appears that eflornithine, a drug used to treat trypanosomiasis, inhibits ornithine decarboxylase, while the aminoglycoside antibiotic/antiprotozoals used to treat leishmaniasis are thought to inhibit protein synthesis.
  • Otherwise a regimen involving the combination of nifurtimox and eflornithine, nifurtimox-eflornithine combination treatment (NECT), or eflornithine alone appear to be more effective and result in fewer side effects.
  • ODC is also an enzyme indispensable to parasites like "Trypanosoma", "Giardia", and "Plasmodium", a fact exploited by the drug eflornithine.
  • In studying the hypothetical reaction mechanism for eflornithine, information collected from radioactive peptide and eflornithine mapping, high pressure liquid chromatography, and gas phase peptide sequencing suggested that Lys-69 and Cys-360 are covalently bound to eflornithine in "T.

  • The drug eflornithine, an inhibitor of ornithine decarboxylase typically used to treat trypanosomiasis, is being investigated as a potential preventive medication in combination with the NSAID celecoxib for treatment of FAP.
  • Nifurtimox/eflornithine is a combination of two antiparasitic drugs, nifurtimox and eflornithine, used in the treatment of African trypanosomiasis (sleeping sickness).
  • Though less effective than nifurtimox with eflornithine in severe disease, fexinidazole has the benefit that it can be taken by mouth.
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