| NOUN | an endothelin receptor | endothelin receptors |
NOUN article.ind sg | pl
22 Übersetzungen
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Anwendungsbeispiele Englisch
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- Targeting this axis with orally available endothelin receptor antagonists may prove efficacious in mimicking the inhibitory role of RhoGDI2 by preventing macrophage infiltration into the micrometastatic niche.
- Endothelin receptor activation mediates strong pulmonary vasoconstriction and positive inotropic effect on the heart.
- A study conducted at Wills Eye Hospital in Pennsylvania found that a potential side effect of medications like macitentan, an endothelin receptor antagonist that is used to treat pulmonary arterial hypertension, can be bilateral cotton wool spots.
- The frame pattern, one of the first spotting patterns to have a DNA test developed, is produced by the Ile118Lys mutation on the equine Endothelin receptor type B gene and when homozygous produces lethal white syndrome.
- An endothelin receptor antagonist (ERA) is a drug that blocks endothelin receptors.
- He kept studying endothelin after moving to the University of Texas Southwestern Medical Center (UTSW) in the United States, for example discovering one of the mechanisms to activate endothelin and that a mutation in endothelin receptor can cause Hirschsprung's disease.
- Clazosentan (INN, trade name Pivlaz) is a drug belonging to the class of endothelin receptor antagonists.
- The main cause of this syndrome is the mutation of the endothelin receptor type B gene (noted as EDNRB).
- Homozygotes for the Ile118Lys mutation on the equine endothelin receptor type B gene have lethal white syndrome.
- However, the successful introduction of SGLT2 inhibitors and endothelin receptor antagonists to the field of renal therapeutics makes the development of PDE5 inhibitors for this purpose unlikely.
- It has potent activity as an endothelin receptor antagonist and anti-osteoporosis agent.
- Zibotentan (INN; development code ZD4054) is an experimental anti-cancer drug candidate in development by AstraZeneca. It is an endothelin receptor antagonist.
- Darusentan (LU-135252; HMR-4005) is an endothelin receptor antagonist.
© dict.cc English-German dictionary 2024
Enthält Übersetzungen von der TU Chemnitz sowie aus Mr Honey's Business Dictionary (nur Englisch/Deutsch).
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