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Anwendungsbeispiele Englisch
- It was shown that pigs could be infected with PRRS virus by several routes of exposure: intranasal, intramuscular, peroral, intrauterine, and vaginal.
- MedImmune received approval from the U.S. FDA for its intranasal novel H1N1 influenza vaccine in September 2009.
- The bioavailability of nafarelin with intranasal administration is 2.8% on average, with a range of 1.2 to 5.6%.
- Intranasal steroids may also be beneficial in patients who do not respond to antihistamines.
- Use of intranasal decongestants (such as oxymetazoline) for more than three days leads to tachyphylaxis of response and rebound congestion, caused by alpha-adrenoceptor downregulation and desensitization.
- Doxepin was under development by Winston Pharmaceuticals in an intranasal formulation for the treatment of headache. Oxetorone is an antimigraine agent.
- An intranasal formulation (Sprix) was approved by the FDA in 2010 for short-term management of moderate to moderately severe pain requiring analgesia at the opioid level.
- The bioavailability of doxylamine is 24.7% for oral administration and 70.8% for intranasal administration.
- In September 2009, a live attenuated intranasal vaccine for the novel H1N1 influenza virus was approved.
- It can be given intramuscular or intranasal depending on the preparations from different manufacturers.
- Dziarski showed that despite their bactericidal activity, mammalian PGRPs have only a limited role in defense against infections. Intranasal application of PGLYRP3 or PGLYRP4 in mice protects from intranasal lung infection with "Staphylococcus aureus" and "Escherichia" "coli", and "PGLYRP1"-deficient mice are more sensitive to systemic infections with non-pathogenic bacteria ("Micrococcus luteus" and "Bacillus" "subtilis").
- It has also been shown that intranasal administration of apotransferrin (aTf) can protect myelin and induce remyelination.
- Testosterone is under development in a low-dose intranasal formulation for the treatment of anorgasmia in women.
- He launched Turing with three drugs in development acquired from Retrophin: An intranasal version of ketamine for depression, an intranasal version of oxytocin, and Vecamyl for hypertension.
- For nocturnal symptoms, intranasal corticosteroids can be combined with nightly oxymetazoline, an adrenergic alpha-agonist, or an antihistamine nasal spray without risk of rhinitis medicamentosa.
- Experimental transmission has succeeded using intranasal aerosol spray or oral drenching.
- Intranasal absorption features low lipophilicity, enzymatic degradation within the nasal cavity, large molecular size, and rapid mucociliary clearance from the nasal passages, which explains the low risk of systemic exposure of the administered drug absorbed via intranasal.
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