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- Similarly, PPIC may confer neuroprotection by forming a complex with CyCAP to activate survival mechanisms and mitigate ischemic damage in the brain.
- Visual deficits, such as agnosia, prosopagnosia or cortical blindness (with bilateral infarcts) may be a product of ischemic damage to occipital lobe.
- Subsequent to this is a period of "myocardial stunning," in which reversible ischemic damage is taking place.
- The splenic flexure is a watershed region as it receives dual blood supply from the terminal branches of the superior mesenteric artery and the inferior mesenteric artery, thus making it prone to ischemic damage in cases of low blood pressure because it does not have its own primary source of blood.
- In the latter, ischemic damage is restricted to the cerebral cortex.
- Given their importance in massive nutrient and electrolyte reabsorption, the proximal tubule and medullary thick ascending limb require significant ATP and are most susceptible to ischemic damage.
- Cerebral areas most susceptible to ischemic damage include the speech and motor cortices, leading to contralateral paralysis, speech, and comprehension loss.
- It is particularly vulnerable to hypoxic or ischemic damage and is one of the first brain regions to show gross changes in cerebral hypoxia.
- Oxycodone overdose has also been described to cause spinal cord infarction in high doses and ischemic damage to the brain, due to prolonged hypoxia from suppressed breathing.
- Storey is an elected fellow of the Royal Society of Canada, Additional applications include insights into hyperglycemia in metabolic syndrome and diabetes, and anoxic and ischemic damage caused by heart attack and stroke.
- It is being confirmed that pumpable ice can selectively cool organs to prevent or limit ischemic damage after a stroke or heart attack.
- Low levels of nitric oxide production are typically due to ischemic damage in the liver.
- The sparing of the pupil is thought to be associated with the microfasciculation of the fibers that control the pupillomotor function located on the outmost aspect of the occulomotor nerve fibres; these fibres are spared because they are outermost and therefore less prone to ischemic damage than are the innermost fibres.
- Surgical treatment is usually required due to the likelihood of stenosis or complete occlusion of the small intestine. Ischemic damage can range from mucosal infarction, which is limited only to the mucosa; mural infarction of the mucosa and underlying submucosa; to transmural infarction of the full thickness of the gastrointestinal wall.
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