Übersetzung für 'lysosome' von Englisch nach Deutsch

lysosome

Lysosom {n}biol.

• These sulfatase enzymes are responsible for breaking down and recycling complex sulfate-containing sugars from lipids and mucopolysaccharides within the lysosome.
• TMEM106B is a transmembrane lysosomal protein that is involved in several key functions for the lysosome. The lysosome is the organelle that clears out debris and unnecessary proteins.
• Variation in the encoded cystinosin protein results in an inhibition or loss in its ability to transport cystine out of the lysosome.
• Lysosome-associated membrane protein 2 (LAMP2), also known as CD107b (Cluster of Differentiation 107b) and Mac-3, is a human gene.
• TRPML1 is believed to channel iron ions across the endosome/lysosome membrane into the cell and so its malfunction causes cellular iron deficiency.

• The founding of Lycia Therapeutics occurred when Bertozzi's group discovered lysosome-targeting chimeras (LYTACs).
• that helps to break down glycogen in the lysosome.
• As a lysosomotropic drug, chloroquine typically accumulates in the lysosome disrupting their degradative function, inhibiting autophagy, and inducing apoptosis through Bax-dependent mechanisms.
• In Gaucher disease, the enzyme glucocerebrosidase is nonfunctional and cannot break down glucocerebroside into glucose and ceramide in the lysosome.
• Initially, GCase was thought to be one of the few lysosomal enzymes that does not follow the mannose-6-phosphate pathway for trafficking to the lysosome.

• Degradation of glycosphingolipids occurs in the lysosome, which contains digestive enzymes in animal cells.
• The lysosome is a compartment within cells that is involved with breaking down large molecules.
• In 2017, the Ragulator was thought to regulate the position of the lysosome, and interact with BORC, a multi subunit complex located on the surface of the lysosomal membrane.
• The intracellular degradation of protein may be achieved in two ways - proteolysis in lysosome, or a ubiquitin-dependent process that targets unwanted proteins to proteasome.
• As the endpoint of endocytosis, the lysosome also acts as a safeguard in preventing pathogens from being able to reach the cytoplasm before being degraded.

• Multivesicular bodies play a large role in the transport of ubiquitinated proteins and receptors to a lysosome.
• After formation, autophagosomes deliver cytoplasmic components to the lysosomes.