Übersetzung für 'opioid agonist' von Englisch nach Deutsch

opioid agonist

Opioidagonist {m}pharm.

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beta-2 agonist <β2-agonist>

Beta-2-Agonist {m} <β2-Agonist>pharm.

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agonist

Agonist {m}biochem.

inverse agonist

inverser Agonist {m}pharm.

receptor agonist

Rezeptoragonist {m}biochem.

dopamine agonist

Dopaminagonist {m}pharm.

adrenergic β2 receptor agonist

Beta-2-Adrenozeptor-Agonist {m} <β2-Adrenozeptor-Agonist>pharm.

short acting beta-agonist

ungeprüft rasch wirksame Beta-2-Sympathomimetikum {n}med.

partial agonist activity <PAA>

partiell agonistische Aktivität {f} <PAA>med.

beta-2 adrenergic agonist

Beta-2-Adrenozeptor-Agonist {m} <β2-Adrenozeptor-Agonist>pharm.

beta-2 (adrenergic) agonist

Beta-2-Adrenergikum {n}pharm.

opioid {adj}

opioidbiochem.

opioid

Opioid {n}biochem.drugspharm.

opioid receptor

Opiatrezeptor {m} [ugs.] [Opioidrezeptor]biochem.

opioid withdrawal

Opioidentzug {m}drugsmed.

opioid intoxication

Opioidintoxikation {f}drugsmed.

Opiatvergiftung {f}drugsmed.

Opiatintoxikation {f}drugsmed.

opioid use

Opioidkonsum {m}med.psych.

non-opioid {adj}

nichtopioidbiochem.pharm.

opioid peptides

Opioidpeptide {pl}biochem.

• Levophenacylmorphan is a morphinan derivative that acts as an opioid agonist.
• Proglumide has also been shown to act as a δ-opioid agonist, which may contribute to its analgesic effects.
• 6-Methylenedihydrodesoxymorphine is a potent μ-opioid agonist, 80x stronger than morphine.
• Enadoline is a drug which acts as a highly selective κ-opioid agonist.
• In contrast both the peptide delta agonist Deltorphin II and the non-peptide delta agonist (+)-BW373U86 actually stimulated respiratory function and blocked the respiratory depressant effect of the potent μ-opioid agonist alfentanil, without affecting pain relief.

• Cyclazocine is a mixed opioid agonist/antagonist related to dezocine, pentazocine and phenazocine.
• Thebacon is an opioid agonist narcotic analgesic of the middle range and a strong antitussive, primarily used in Europe, although it is no longer in common use.
• The substitution of certain bulky groups on nitrogen 17 converts an opioid agonist into an opioid antagonist, the most important of which is naloxone, a non-selective opioid antagonist with no opioid agonist properties whatsoever ("silent" antagonist).
• MC5 is a mu-opioid agonist but not delta-opioid agonist, with EC50 at the mu-opioid receptor of 0.545 μM (vs 0.194 μM for tianeptine).
• The authors point out that the nalbuphine moiety is approximately ten times more pharmacologically potent than the mixed opioid agonist/antagonist butorphanol on an "antagonist index" scale which quantitates the drug's ability to act both as an analgesic (via opioid KOR agonism) as well as a MOR antagonist.

• Several opioids, particularly levorphanol, methadone and ketobemidone, possess NMDA receptor antagonism in addition to their µ-opioid agonist properties.
• Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for chronic pain and also for opioid dependence.
• Opioid agonist therapy (OAT) is the medical procedure of using a harm-reducing opioid that produces significantly less euphoria, such as methadone or buprenorphine to reduce opioid cravings in people who use illegal opioid, such as heroin; buprenorphine and methadone are taken under medical supervision.
• amphetamine is often dispensed as racemic salts while the more active dextroamphetamine is reserved for refractory cases or more severe indications; another example is methadone, of which one isomer has activity as an opioid agonist and the other as an NMDA antagonist.
• Dextromethorphan (the stereoisomer of levomethorphan, a semi-synthetic opioid agonist) and its metabolite dextrorphan have no opioid analgesic effect at all despite their structural similarity to other opioids; instead they are potent NMDA antagonists and sigma 1 and 2-receptor agonists and are used in many over-the-counter cough suppressants.

• δ-opioid agonists can produce respiratory depression at very high doses, at lower doses they have the opposite effect.