Übersetzung für 'regulatory T cell' von Englisch nach Deutsch

regulatory T-cell <Treg>

regulatorische T-Zelle {f} <TReg>biol.med.

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natural killer T cell <NKT cell>

natürliche Killer-T-Zelle {f} <NKT-Zelle>med.

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T cell

T-Zelle {f}biol.

T-helper cell

T-Helfer-Zelle {f}biol.

T-Helferzelle {f}biol.

helper T cell

T-Helferzelle {f}biol.

T-Helfer-Zelle {f}biol.

T-suppressor cell

T-Suppressorzelle {f}biol.

suppressor T-cell

T-Unterdrückerzelle {f}biol.

T-cell recruitment

T-Zell-Rekrutierung {f}biol.

memory T cell

Gedächtnis-T-Zelle {f}biol.

T-cell precursor

T-Vorläuferzelle {f}biol.

T-cell receptors

T-Zell-Rezeptoren {pl}med.

cytolytic T cell <Tc>

T-Killerzelle {f} [veraltet] [cytotoxische T-Zelle] <Tc-Zelle>biol.

T cell receptor <TCR>

T-Zellenrezeptor {m} <TCR>biochem.

cytotoxic T cell <CTC>

cytotoxische T-Zelle {f} <CTL>biol.

T cell receptors <TCRs>

T-Zellenrezeptoren {pl} <TCR>biochem.

central memory T-cell <TCM>

zentrale T-Gedächtniszelle {f}biol.

effector memory T-cell <TEM>

Effektor-T-Gedächtniszelle {f}biol.

monoclonal T cell receptors <mTCRs>

monoklonale T-Zell-Rezeptoren {pl} <mTCR>biochem.

monoclonal T cell receptor <mTCR>

monoklonaler T-Zell-Rezeptor {m} <mTCR>biochem.

• Alteration of regulatory T cell activity: Suppressing regulatory T cell activity following injury can allow a more robust autoimmune response to take place.
• The cause of selective IgM deficiency remains unclear, although various mechanisms have been proposed, such as an increase in regulatory T cell functions, defective T helper cell functions and impaired terminal differentiation of B lymphocytes into IgM-secreting cells among others.
• C3aR has been shown to be necessary for TH1 cell generation and regulates TH1 IL-10 expression, while an absence of active C3aR on dendritic cells upregulates regulatory T cell production.
• LTCI increases the immune response to foreign antigens and dampens the immune-mediated response to self-antigens by increasing the number of precursors of a regulatory T-Cell population.
• Scientists at the Istituto Nazionale dei Tumori in Milan, collaborating with the Triebel group, showed that LAG3 defines a potent regulatory T cell subset that shows up more frequently in cancer patients and is expanded at tumor sites.

• Male homozygotes showed an increased susceptibility to "Salmonella" infection, while homozygotes of both sex had decreased IgG1 and decreased regulatory T cell and NK cell numbers.
• "In vitro", TSLP directs the maturation of dendritic cells, and increases the ability of dendritic cells to convert naive thymocytes to a Foxp3+ regulatory T cell lineage.
• Immunodysregulation polyendocrinopathy enteropathy X-linked (or IPEX) syndrome is a rare disease linked to the dysfunction of the gene encoding transcription factor forkhead box P3 (FOXP3), widely considered to be the master regulator of the regulatory T cell lineage.
• In addition to Foxp3's role in regulatory T cell differentiation, multiple lines of evidence have indicated that Foxp3 play important roles in cancer development.
• Alexander Rudensky (born August 21, 1956) His lab continues to investigate the molecular mechanisms underlying regulatory T cell activity, and the role these cells play in autoimmunity, tumor immunity, and immunity to infections.

• STAT5 is important for regulatory T cell (Treg) differentiation and function, which may explain why many STAT GOF patients have low Tregs.
• Leonard Moise discovered regulatory T cell epitopes, called “Tregitopes”, that are shown to activate regulatory T cells and suppress the immune response.
• The resolution of the I-J paradox involves a process of mutual selection (or "co-selection") of regulatory T cells and helper T cells, meaning that (a) those regulatory T cells are selected that have V regions with complementarity to as many helper T cells as possible, and (b) helper T cells are selected not only on the basis of their V regions having some affinity for MHC class II, but also on the basis of the V regions having some affinity for the selected regulatory T cell V regions.
• Similar to other T cells, regulatory T cells develop in the thymus.