Übersetzung für 'thyroglobulin' von Englisch nach Deutsch

thyroglobulin <Tg>

Thyreoglobulin {n} <TG>biol.

• The drug acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland.
• On immunohistochemistry testing, ATC is usually positive for the keratin, p53, and PAX8 proteins and is negative for thyroid transcription factor-1, thyroglobulin, and calcitonin.
• ... folded proteins of known molecular weight), and a sample containing a very large molecule such as thyroglobulin to determine the void volume.
• PTU inhibits the enzyme thyroperoxidase, which normally acts in thyroid hormone synthesis by oxidizing the anion iodide (I−) to iodine (I0), facilitating iodine's addition to tyrosine residues on the hormone precursor thyroglobulin.
• Ctenitoxins consist of two repeats of thyroglobulin type I domain (Thyroglobulin type-1 1 and Thyroglobulin type-1 2) and a signal peptide.

• Examples of ATE1 targets which have been identified include ornithine decarboxylase., thyroglobulin, insulin, and neurotensin.
• Salvatore's early research at the NIH focused on the synthesis and structure of thyroglobulin.
• She discovered in 1969 that thyroglobulin undergoes carbohydrate modifications, part of a class of proteins known as glycoproteins.
• Elimination of such autoantibody interferences drove the adoption of SISCAPA as an alternative to immunoassays for clinical measurement of thyroglobulin as a marker of thyroid cancer recurrence in patients who exhibit anti-thyroglobulin autoantibodies.
• They purified anti-thyroglobulin antibody from their serum and were able to conclude that these sick patients had an immunological reaction to human thyroglobulin.

• Follicular cells take up iodide and amino acids from the blood circulation on the basolateral side, synthesize thyroglobulin and thyroperoxidase from amino acids and secrete these into the thyroid follicles together with iodide.
• Mouse models of autoimmune thyroiditis showed that a semi-mature phenotype of dendritic cells is maintained after mouse thyroglobulin immunization in GM-CSF treated but not control mice.
• In the clinical laboratory, thyroglobulin testing can be complicated by the presence of anti-thyroglobulin antibodies (ATAs, alternatively referred to as TgAb).
• Thyroglobulin antibodies are specific for thyroglobulin, a 660kDa matrix protein involved in the process of thyroid hormone production.
• Since iodine is an inorganic compound, and is being attached to thyroglobulin, a protein, the process is termed as "organification of iodine".

• Within the thyroid follicular cell, thyroglobulin is hydrolyzed to form thyroid hormones and mono- and diiodotyrosine.