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Usage Examples English
- Both Phase II studies indicated a tolerability profile for solabegron that was similar to placebo. This drug does not bind to acetylcholine receptors so side effects are expected to be minor.
- Within one review prulifloxacin was stated to have a similar tolerability profile to that of ciprofloxacin.
- In pediatric population with acute bronchitis, tracheobronchitis and pneumonia, erdosteine showed a significantly high reduction in cough intensity and improvement of clinical symptoms, with very good tolerability.
- The multicenter, randomized, double blind, placebo-controlled Phase IIb clinical study on 150 patients was designed to evaluate the efficacy, safety and tolerability of the therapy with clinically isolated syndrome (CIS) and early relapsing-remitting MS (RR-MS) patients.
- Dersimelagon (MT-7117) is an orally administered MC1R agonist being tested in phase 3 clinical trials to evaluate safety and tolerability in patients with erythropoietic protoporphyria or X-linked protoporphyria.
- Used to increase tolerability of bitter medication or merely to compel consumption, medicated candies or sugar-coated pills can be referred to as dragées.
- Trimetazidine has been treated as a drug with a high safety and tolerability profile.
- Clinical evidence is available to support a particularly good profile in terms of gastrointestinal tolerability.
- A phase II trial for Alzheimer's disease, PEGASUS, confirmed the safety and tolerability of sodium phenylbutyrate/ursodoxicoltaurine.
- A Phase II open-label clinical study for long-term evaluation of efficacy, safety, tolerability, and pharmacokinetics of RT001 in the treatment of infantile neuroaxonal dystrophy started in the Summer 2018.
- Drug tolerance should not be confused with drug tolerability, which refers to the degree to which overt adverse effects of a drug can be tolerated by a patient.
- Dose de-escalation below the starting doses in case of poor patient's chemotherapy tolerability applies to cyclophosphamide only.
- This improved tolerability and compliance in turn reduces risk of developing dangerous drug resistance.
- In the treatment of psychiatric conditions including bipolar depression, a form of chronotherapy combining intermittent sleep deprivation and morning bright light has shown efficacy and relative tolerability in a number of controlled studies.
- PBT2-203 (Reach2HD) was a 6-month safety, tolerability and efficacy study in HD.
- In July 2014, Molecular Partners initiated a first-in-human study to investigate the safety, tolerability and blood levels of MP0250, a second DARPin candidate, in patients with cancer.
- Drug tolerability should not be confused with drug tolerance, which refers to subjects' reduced reaction to a drug following its repeated use.
- A favorable tolerability profile for troxipide was reported by 95.45% of the investigators as compared to 65.45% for ranitidine while favorable tolerability profile was reported by 93.67% of the patients for troxipide and 64.55% for ranitidine.
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Contains translations by TU Chemnitz and Mr Honey's Business Dictionary (German-English only).
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