Translation for 'autophagy' from English to Russian

autophagy

аутофагия {ж}биол.

• Given ULK1's role in autophagy, many diseases such as cancer, neurodegenerative disorders, neurodevelopment disorders, and Crohn's disease could be attributed to any impairments in autophagy regulation.
• Enhanced activity of PFKFB3 accelerates ROS production as an end product of glycolysis, and thus increases autophagy. Likewise, inhibition of PFKFB3 has been found to induce autophagy.
• TBK1 promotes autophagy involved in pathogen and mitochondrial clearance.
• This relationship between autophagy and BNIP3 is widely supported in many studies.
• Autophagy then occurs at an accelerated rate. In autophagy, cells cannibalize critical molecules to produce amino acids for gluconeogenesis.

• Trehalose has long been known as an autophagy inducer that acts independently of mTOR.
• A third finding is the discovery of a therapeutic approach that ERK inhibition increases pancreatic cancer addiction to autophagy.
• He found that cell death in replicative crisis is executed by the autophagy machinery.
• Autophagy is executed by autophagy-related (Atg) genes. Prior to 2003, ten or more names were used, but after this point a unified nomenclature was devised by fungal autophagy researchers.
• Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly.

• Proteins that are degraded by chaperone-assisted selective autophagy include pathogenic forms of the Huntingtin protein, which cause Huntington's disease.
• In a 1999 paper in Nature, she proposed that autophagy was linked to tumor suppression.
• Generally, autophagy includes three small branches, which are macroautophagy, microautophagy, and chaperone-mediated autophagy.