Translation for 'clathrin' from English to Russian

clathrin

клатрин {м}биол.биохим.

• The protein contains a clathrin box, with two identified clathrin-binding motifs, and is involved in vesicle-trafficking.
• Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits.
• AP2 facilitates the assembly of clathrin lattices when endocytosis needs to occur, by aggregating together with other AP2 complexes, in their active conformation.
• Amphiphysin is a brain-enriched protein with an N-terminal lipid interaction, dimerisation and membrane bending BAR domain, a middle clathrin and adaptor binding domain and a C-terminal SH3 domain.
• However, in higher eukaryotes there are several conserved motifs such as the clathrin-binding motifs which bind clathrin heavy chain, these motifs flank a cluster of up to eight DP repeats which bind to AP2.

• AP180 is a protein that plays an important role in clathrin-mediated endocytosis of synaptic vesicles.
• The best characterized type of vesicle is the clathrin coated vesicle (CCV).
• In this process, the bound LCGR-hormone complex binds arrestin and concentrates in clathrin coated pits.
• Clathrin-mediated endocytosis is the only pathway dependent on both clathrin and dynamin.
• The nucleation complex was formed through the interaction of VPS complex with GTP-activated Rab7 with clathrin, clathrin-adaptors and various binding proteins.

• LDL receptors are inserted into the plasma membrane and diffuse freely until they associate with clathrin-coated pits.
• In Clathrin-dependent endocytic pathways, endosomes budding from the cell membrane into the cell will form in clathrin pits, and be coated by clathrin triskelions.
• While working with Tomas Kirchausen, she created an animation on clathrin-mediated endocytosis, researching how clathrin triskelions operated and assembled on the inner surface of the plasma membrane to invaginate an extracellular particle.
• Her interest was in clathrin-coated vesicles that binds to cargo.
• Clathrin is a large, soluble protein composed of heavy and light chains.

• These vesicles have specific coat proteins (such as clathrin or coatomer) that are important for cargo selection and direction of transport.
• Virions enter the host cell is achieved by attachment to host receptors, which may be mediated by clathrin-mediated endocytosis or clathrin-independent dynamin-dependent endocytosis.
• Clathrin-independent carriers (CLICs) are prevalent tubulovesicular membranes responsible for non-clathrin mediated endocytic events.