Translation for 'cohesin' from English to Russian

cohesin

когезин {м}биол.биохим.

• The dockerin's binding partner is the cohesin domain, located on the scaffoldin protein.
• Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.
• Centromeric cohesin and H2A-pT120 specify two distinct pools of Sgo1-PP2A at inner centromeres and kinetochores respectively, while the CDK1/cyclin B phosphorylation on Sgo1 is essential for Sgo1-PP2A to protect centromeric cohesin, not only for bringing PP2A to cohesin, but also physically shield out the negative regulator WAPAL from cohesin.
• When a cell enters mitosis, Sororin is phosphorylated causing it to dissociate from cohesin meaning WAPL can remove cohesin from the DNA.
• Also, Chk1 has been shown to be activated by the Scc1 subunit of the protein cohesin, in zygotes.

• Cohesin is a protein complex that mediates sister chromatid cohesion, homologous recombination, and DNA looping.
• Using temperature-sensitive mutants of the APC/C he found several genes which are required for sister chromatid cohesion which we now know encode subunits of the cohesin complex.
• Andrea Pauli's doctoral research focused on cohesin, a protein complex initially known for its essential role in holding sister chromatids together during cell division.
• Insulated neighborhoods are defined as chromosome loops that are formed by CTCF homodimers, co-bound with cohesin, and containing at least one gene.
• Establishment of cohesion refers to the process by which chromatin-associated cohesin becomes cohesion-competent.

• Unlike in mitosis, only the cohesin from the chromosome arms is degraded while the cohesin surrounding the centromere remains protected by a protein named Shugoshin (Japanese for "guardian spirit"), what prevents the sister chromatids from separating.